KMID : 0032220210330020186
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Annals of Dermatology 2021 Volume.33 No. 2 p.186 ~ p.189
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A Case of Herpes Zoster Granulomatous Dermatitis: Report of Wolf's Isotopic Response
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Yoon Ji-Ha
Jang Ye-Ji Park Eun-Joo Kim Kwang-Joong Kim Kwang-Ho
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Abstract
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Wolf's isotopic response refers to the occurrence of a novel skin disease at the site of a preceding treated or untreated skin disease. Although the most common preceding skin disease was found to be herpes zoster (HZ), HZ-related dermatological phenomena are not well known in the literature. We report a case of HZ granulomatous dermatitis in a 77-year-old female with a previous history of hypertension, diabetes mellitus, chronic kidney disease, and HZ. She presented with a 3-month history of a pruritic skin lesion on her right thigh. The location of the lesion was consistent with a previous HZ site. Histopathological examination revealed lympho- histiocytic infiltration in the superficial dermis, forming a granulomatous structure. Based on clinical and histopathological findings, we made a diagnosis of granulomatous dermatitis at a previous HZ site. We assumed that the lesion arose from an isotopic response of Wolf. The patient was treated with topical steroids for 3 months and showed clearance of the lesion and symptom. We suggest that treatment should be based on the individual disease, which in our case was topical steroid.
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KEYWORD
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Dermatitis, Herpesvirus 3, Human
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